Related Clues:

• Start of a long drive?
• Souvenir shop item, for short
• Response to a pickup line, perhaps
• Palmer's peg
• It's produced in the islets of Langerhans
• Cross it (and dot your i's while you're at it)
• Duel preliminary
• Rebuke
• Smack in the face
• Green peg
• Winter ailment
• Billiards bounce
• Golf ball peg
• Plumbing fitting
• Response to an affront