Related Clues:
- Powerful empire, once
- Colosseum's city
- Setting for Hawthorne's 'The Marble Faun'
- The eternal city
- Pantheon's city
- 'The Last Supper' location
- City founded by a twin, in myth
- Where Cassius Clay earned an Olympics gold medal
- Broadway composer-lyricist Harold
- Italy site found in the four longest Across answers
- City with a country inside it
- Ambrosian Library setting
- Home of the Spanish Steps, counterintuitively
- City where it's OK to say 39-Down
- Only city with a country inside of it