Related Clues:

• 'This does not look good!'
• 'What happened now?!'
• Grinchesque exclamation
• Dash perhaps part of GP's email address?
• "How disappointing"
• Endlessly slow, turning up? Blast!
• Panicked exclamation
• “This is terrible!”
• 'That's terrible news!'
• 'This CAN'T be happening'
• 'Oh, nerts!'
• Words from Professor Higgins, and where you’ll find the starts of 17-, 26-, 35- and 48-Across
• 'I'm panicking!'
• "Aw, nuts"
• 'That's not gonna be good!'