Related Clues:

• One-liner, often
• Marx observation
• A crew sick at sea? That's a joke!
• Words of Hope
• Many a tweeted remark
• Witticism ... or, literally, a description of the answer to each of the four starred clues?
• Short witticism
• Advisable to take drug? That's a joke
• Sparkling remark
• Joke told about end of family's split
• Learned conversation? That's a joke
• You may ask why is cocaine a cause of mirth?
• Funny piece of equipment
• Enlightened, to take addictive drug? That's a joke!
• Sally's experienced enough to yield to pressure