Related Clues:

• Source of ruin
• Affliction
• Source of trouble
• Poison
• Ill bringer
• Cause of misery
• Thorn in one's side
• Witch's brew
• Undoing
• Thorn in the flesh
• Cause of distress
• Blight
• Cause of one's undoing
• Anathema
• Cause of ruin