Related Clues:

• Source of worry
• Migraine
• Difficulty - dispute
• Severe problem
• Harass — grief
• It may be unbearable
• Vexing situation
• Harass, bother
• What a dolorimeter measures
• Nuisance bursting with good health running around ship
• Pain in the neck to crown a revolutionary
• Bread, in Bruxelles
• Suffering's partner, in court
• "I feel your __"
• Suffering of body or mind