Related Clues:

• Concerning
• Worrying
• Nerve-racking
• Troublesome
• Hard to bear
• It "gives you something to do, but it gets you nowhere": Glenn Turner
• Fretting
• In a stew
• Taxing
• Distressing, perturbing
• Distressing
• Taxing is frustrating
• It's far from calming to emphasise the possibility of flu
• Fretting, anxious
• Losing sleep over row leads to crying without Charlie