Related Clues:

• Spine-tingling
• Codeine, for one
• Source of relief
• Narcotic
• Poppy plant derivative
• Downer
• Inoffensive
• Chloral hydrate, e.g.
• Calmer
• Cough medicine ingredient
• Pain-relieving
• It's a relief
• Relaxant
• Opium compound
• Sleep-inducing