Related Clues:

• Heartbreak
• Word in a Charlie Brown phrase
• Hassle, slangily
• Heavy heart
• Hard time, informally
• Annoyance, so to speak
• Deep sorrow
• Deep sadness
• Reaction to personal loss
• Bereavement
• Great sorrow
• "Good __!": Charlie Brownism
• "Good ___!" ("Peanuts" exclamation)
• "Good ___!"
• Big hassle, so to speak