Related Clues:

• Is that so?
• Inflammation (Suff.)
• Response to a surprising statement
• 'Are you kidding me?'
• Senior attachment?
• Reply to 'Really?'
• Genuine for Shakespearean king to make comeback
• Brief affirmation
• 'That so?'
• Medical office closing?
• Tendon attachment?
• ''You know how __''
• "No kidding"
• "You know how ___"
• Answer to 'That so?'