Related Clues:

• Main road with some reversing tyre tracks
• Lose the head in traffic close to highway - an important major road
• Throughway, e.g
• Queen carried in pretentiously refined vessel
• -hipping rout-?
• Blood vessel that transports oxygenated blood
• Major thoroughfare or blood vessel
• Vein's cousin
• Reportedly understand how to make main course?
• The aorta, for instance
• Inland passage
• Ocean passage