Related Clues:

• Mature, as wine
• See 34 Across
• Reason to retire
• Fatigue factor
• Yellow or gray
• Sore point, for some
• The big 4-0, for example
• Dr. Ruth's subject
• Book by Madonna
• Word with information, new or old
• Birth certificate datum
• James Brown hit '___ Machine'
• Bouncer's concern
• Become ripe
• Talk show topic