Related Clues:

• Extreme sadness
• Intense sorrow
• Swiss play in hand. Or rather, at hand
• Distress caused by composer changing final note
• Feeling of devastated figure missing out on university?
• Trouble's good and short in the absence of the British
• Great mourning
• A dog-end set fire to, causing misery
• Trouble close to raging fire out of control
• Figure United's lost badly creating despair
• Great sadness
• Great sorrow at someone's death
• Specialty of some counselors
• Real unhappiness will occur if Reg breaks down
• "Good __!"