Related Clues:
- Sedative drug
- Endorphin, e.g.
- Drug that dulls the brain
- Drug from poppies
- Poppy derivative
- Subject of the Rolling Stones' 'Mother's Little Helper'
- Morphine, for one
- Narcotic drug
- Endorphin, basically
- Mind duller
- Muscle relaxant
- Religion, in an oft-quoted metaphor
- Stimulant's opposite
- Anxiety-relieving drug
- It's a downer