Related Clues:

• Vex a lot
• Bother greatly
• Persistently irritate
• Bug the hell out of
• Rile or rankle
• Reaction to a snub, maybe
• The Hulk's catalyst
• Be a nuisance to
• Be a pain to
• Cause of an outburst
• Red-seeing state
• ___ management
• Do some button-pushing, so to speak
• Get someone's dander up
• 37-Across