Related Clues:

• Plenty ticked, with 'up'
• ___ up (agitated)
• Riled (up)
• -- up (agitated)
• Highly excited (with ''up'')
• Not gay, slangily
• Plenty steamed, with 'up'
• Plenty worked (up)
• Different: Prefix
• Ruffled, with 'up'
• Agitated, with 'up'
• All ___ up (agitated)
• Riled
• Aggravated (with up)
• Prefix with -geneous