Related Clues:

• Angry dog, at times
• Mosquito or mole, e.g.
• Fly, perhaps
• 17-Across in the neck
• Annoying bug
• Ankle-___
• Irksome one
• Pain in the ass
• Dog to avoid
• One who 26-Across
• Destructive insect or nuisance
• A nuisance - step on it
• Troublesome man or animal
• He who is sometimes bit
• He who may be bit