Related Clues:

• On vacation, perhaps
• Straying from the course
• "On" antonym
• Deviating from the straight and narrow
• Awry or away
• Ecstasy over Republican tirade going wrong
• Knight-___
• Like an overthrow, say
• Word that can follow the first parts of 17- and 60-Across and 11- and 27-Down to form baseball terms
• Tub-thumper's cycling, always on the move
• Stingray
• "Kiss You ___" Scissor Sisters
• "Let's Call the Whole Thing ___"
• Prince "Get ___"
• The Donnas "Take It ___"