Related Clues:

• "What's up, ___?" (Bugs Bunny catchphrase)
• Scales to go up: Yankee is heavy
• G.P., for one
• Medic's white fish heading westwards
• Physician, briefly
• Rx provider
• ER pro
• Sleepy housemate
• __ Hopper: "The Muppet Movie" villain
• MS Word file