Related Clues:

• Banner spangler
• Change direction
• Betelgeuse, e.g.
• Leader
• Boss (with ''head'')
• Big name
• Business magnate
• Oft-heard word in a portrait studio
• Top dog
• With 50- and 53-Down, apt title for this puzzle
• High muck-a-muck
• Notable
• Finger
• Constellation component
• Betelgeuse, for one