Related Clues:

• Moan and groan
• Pet ___
• React to a pun
• Strengthen, with 'up'
• Bad pun response
• Strike, essentially
• Rile
• Ailment
• Bony fish
• Response to a weak joke, perhaps
• Lamentation
• Pained cry
• Plaintive sound
• Vegan's taboo
• Kick, in a way