Related Clues:

• Impudent nobody
• Vexatious one
• Little shit
• Irksome type
• Mosquito or fly
• Gnat, often
• Bug you want to swat
• Source of exasperation
• Irritating sort
• Aphid, to a fruit tree
• Dennis the Menace, to Mr. Wilson
• Mosquito or mole, e.g.
• Fly, perhaps
• 17-Across in the neck
• Annoying bug