Related Clues:

• "__-Tac-Dough": TV game show
• Sign of nerves in a politician
• Rapid blinking, e.g
• Cause of writer's cramp, often
• It may be nervous
• One may be nervous
• Cause of writer's cramp
• What twitch regularly shows?
• With 40- and 43-Across, game that's been played in each of this puzzle's corners
• Rapid eye blinking, e.g
• ___ tac toe
• ''___ Tac Dough''
• ''___ Tac Dough'' (quiz show)
• ___-Tac-Toe
• First word of a game with X's and O's