Related Clues:

• Very painful
• Saddle irritation
• In an angry mood
• Word with ''thumb'' or ''loser''
• Pimple
• Regretting a workout, say
• Harboring a grudge
• Not happy at all
• Inflamed, maybe
• In some physical distress
• In need of shiatsu
• Needing relief
• Throbbing
• Aggrieved
• In need of liniment