Related Clues:
- Fly in the ointment when top removed for the allergic reaction
- Something you might scratch
- Inflammation-causing substance such as pollen
- Desire for what you might have got with 3 down
- Mosquito bite aftermath
- Long grass totally pointless
- Two of the Kings of Ireland, one upset by heartless taunt that's a thorn in someone's side
- Buried in breadfruit, chrysalides are dying
- Have a strong desire (for something)
- Computers etc starting to cause headaches and irritation
- Seven-Year ___ , 1955 film starring Marilyn Monroe with Tom Ewell
- Reason to think you might have the measles
- Result of a bedbug bite
- Problem doing without heroin for long
- Back-scratcher target