Related Clues:

• 38-Down, e.g
• Crop threat
• Little brother, to an older sibling, say
• Constant nuisance
• Recurring pain?
• Slug, e.g
• Insecticide victim
• Mosquito or gnat
• Irking insect
• Mole, to a suburbanite
• Annoying person or bug
• Irritating one
• Steady annoyance
• Garden headache
• Nuisance; half a European capital