Related Clues:

• Cheese off
• Really tick off
• Lire (anag)
• Get on someone's back
• Honk off
• Rub up the wrong way with loud music to go off
• Make really mad
• Ruffle the feathers of
• Bug, and then some
• Irritate considerably
• Anger (with "up")
• Incite anger
• Ladder, part 6
• Make agitated
• Really anger