Related Clues:
- Vexing situation
- Reason to call 911
- Pain in the neck to crown a revolutionary
- Heartbeat quickener
- Double lives after credit crunch
- Is found twice behind credit crunch?
- Hangover symptom
- Pest on top of everything else is painful
- Migraine, e.g
- Cause of worry
- Emergency (in midlife?)
- Cold river has Oxford crew in deep water
- Serious situation
- Desperate situation
- The principal pain?