Related Clues:

• Get on someone's back
• Honk off
• Rub up the wrong way with loud music to go off
• Make really mad
• Ruffle the feathers of
• Bug, and then some
• Irritate considerably
• Anger (with "up")
• Incite anger
• Ladder, part 6
• Make agitated
• Really anger
• Cause a stir
• Word ladder, part 2
• Needle or nettle