Related Clues:

• Extreme and difficult to endure
• Seemingly hopeless
• It's disastrous to first think local newspaper is in charge
• Cut off sweetheart from what's difficult to endure
• Serious diamonds come from Ireland
• Terribly sad and distressing
• More than unfortunate
• Like many of Shakespeare's protagonists
• Like some bears' market predictions
• Ominous; very bad
• Most pitiable
• Desperate; dreadful
• It's hard to part with drug
• Plain, hard
• Nervous reaction limiting student frolics is very sad