Related Clues:

• Try too hard
• Burn, say
• Work one's fingers to the bone
• Break one's back, so to speak
• One of Churchill's four offerings
• Carry to extremes
• Exert to excess
• Galley drudge
• Exhausting effort
• Group of viruses
• Not practice moderation
• Mishandling
• Go too far (with "it")
• Misappropriation
• Sweat blood