Related Clues:

• Lost cause
• Hopeless case
• You can kiss this person goodbye
• Dead duck
• Person beyond help
• One who's done for
• Irretrievable thing
• Hopeless soul
• One who hasn't much time left
• Bad choice to bet on
• Doomed one
• One beyond hope
• One whose goose is cooked
• Toast, after 'a'
• One for whom there's no hope