Possible Clues:

• Ancient region east of Adriatic Sea
• Old region along east coast of the Adriatic
• Setting for Shakespeare's "Twelfth Night"
• Ancient region badly needing road and railway set-up
• Shakespearean night setting airily changed, and extra line introduced
• Poor and jaunty, turned up in Orsino's dukedom
• Black out film extracts about drug repeatedly? On the contrary
• Ancient Adriatic region; Twelfth Night setting
• Country of 'Twelfth Night'
• Wrongly dismissive about setting at start of Twelfth Night