Possible Clues:

• Reason for using a heating pad
• Something necessary for gain, they say
• Discomfort cause
• Reason to keep rubbing one's back
• The distress of hen parties without Esther
• Royal ___
• Affliction I found aboard vessel
• 6 movie from 2019 starring Antonio Banderas
• Suffering something picked up from boulangerie?
• Counterpart of pleasure