Possible Clues:

• Dracula, for one
• Halloween costume choice
• Bloodsucker stakeholders could kill?
• Transylvanian bloodsucker
• Hammer staple?
• Against a politician with anger -- one that's after blood
• Sucker who shows a lust for life's essential?
• Creature who might disagree with the saying at the ends of 17-, 22-, 48- and 56-Across
• It drinks the blood of the living by night
• Blood-sucker (bat)