Possible Clues:

• __ Major (the Big Dipper)
• She's a bear
• "Major" animal of the sky
• ___ Major (''The Great Bear'')
• With 45-Down, home of the Big Dipper
• Labour saving environment for stars
• Star group, following 17 or 20, taking part in tours abroad
• 'Major and Minor, constellations (4)'
• Bear people look up to
• -- Major, constellation also known as the Great Bear