Possible Clues:

• "... from New York!" show, briefly
• Weekend show with Aidy Bryant, to fans
• Betty White recently hosted it
• Andy Samberg show, for short
• Variety show since 1975, briefly
• Popular skit show, for short
• It's shot at 30 Rock
• "Weekend Update" prog.
• NBC staple since the '70s
• NBC staple for 45 years