Possible Clues:

• That's just a bloody transplant
• Different attitude after transplant
• It makes one think differently about the earth, for instance
• Shift in one's feelings (3 words)
• Tom Petty song
• New view of earth?
• What a bloody alteration by transplant, perhaps
• Attitude alteration
• Profound alteration in outlook or opinion
• A new 35 across by 9 down the 8 down