Possible Clues:

• Texas city with a Jalapeno Festival
• Texas A&M International city
• Texas city, capital of the short-lived Republic of the Rio Grande in 1840
• Hollywood makeover, say?
• City about 560 miles north of Mexico City
• Texas city with an annual Jalapeno Festival
• City with an annual Jalapeno Festival
• 35 Across city on the Rio Grande
• Capital of the onetime Republic of the Rio Grande
• Home of the annual Jamboozie music festival