Possible Clues:

• From a US state, capital Des Moines
• Nothing must stop single white American
• John Wayne or Buffalo Bill, by birth
• Hawkeye, e.g.
• Des Moines denizen
• Any resident of 46-Across
• Des Moinesian or Davenporter
• Johnny Carson, for one
• Davenport shopper, probably
• Statesman pale beneath the moon