Possible Clues:

• Describing some champagne, Capone was really cruel
• British ultra-sloshed and barbarous
• Harsh routine in research facility set up
• Harsh, like Buffalo winters
• Unsparing curbing of habit by party from the right
• Coarse description of some wines by a learner
• Punishingly hard
• Frank's very dry with a learner
• Let in/off bullet train by Savage, in manner of speaking?
• Animal research facility about to introduce a tedious course