Possible Clues:

• Loyal friend with two more legs than you
• Any one of man's best friends
• Beagle, e.g
• See 20-Across
• Goofy, e.g.
• Warrant "___ Eat ___"
• See 57-Down
• Animal in the game 'Beagle or Bagel'
• Walker's charge
• Sick as a ____