Possible Clues:

• Medicine chest item
• Stuff from tube osteopath ordered after start of treatment
• It's applied with a brush
• Signal to in both directions, beginning to point quickly?
• Medicine-chest item
• Besides the previous filling, might this prevent another?
• Canine protector
• The potato's mashed — put it in your mouth!
• It's also done to break into the contents of tube
• Tate photos twisted in a tube might save you a filling?