Possible Clues:

• Bitter chap's under terrible strain
• Running strain on man is severe
• A part of hospital employing twists of cotton in medical preparation
• Cutting a queue by hospital department
• A chap keeping no end of racehorses is sharp
• One cord and ten more may be somewhat severe
• Acordent, perhaps, to its being so sharp
• Cord used in a hospital department for checking bleeding
• Severe - checking the flow of blood
• One cord and another knotted ten to make this sharp