Possible Clues:

• One who doesn't fit in
• Flounder -- when caught out of place? (1,4,3,2,5)
• Topic of many comedies
• When left high and dry one definitely flounders (1,4,3,2,5)
• Odd one out, as fourth wife to a rip (1,4,3,2,5)
• Crocodile Dundee in Manhattan, say
• Flounder when caught? One certainly does (1,4,3,2,5)
• Catch one feeling out of place (1,4,3,2,5)
• Misfit, proverbially
• Someone not at home saw a fortieth UFO -- possibly! (1,4,3,2,5)