Possible Clues:

• Absence of sense of pain
• Incontinent — angel contrived to achieve painlessness
• After treatment, angel, Japan-based perhaps, gets relief from pain
• Leg broken, an enormous area for bandaging that's painless
• Insensitivity to pain
• A gel NASA developed includes iodine for pain relief
• Distributed as a genial way not to feel pain
• Much of East Anglia redeveloped — effect of numbers?
• Insensitive state drivers commandeering a single convertible
• Strange angle adopted by continent showing lack of feeling