Possible Clues:

• Relief of pain
• Pain relief
• Inability to feel pain in extravagant Alien saga
• Painstaking medical procedure?
• Insensibility to pain
• Most of East Anglia redeveloped -- effect of numbers?
• Inability to feel pain about angel in Asia
• As a linage (anag) — insensibility to pain
• Treating again with laser almost complete lack of pain
• The painlessness of drivers accepting leasing arrangement