Possible Clues:

• Like very good, so up not to be fired
• Like the finest, so it's up never to be fired
• Fire-resistant material
• Fire-resistant mineral
• A distress call about most dangerous material
• Stuffing that need not get out of the kitchen?
• Fireproofing construction mineral banned in many countries
• 'Fireproof substance, dangerous to health (8)'
• A distressed call for installation of the greatest domestic hazard?
• A request for help about top cause of respiratory disease