Possible Clues:

• You, south of the border
• Spanish 101 word that's an anagram of DUETS
• Spanish counterpart of the French 'vous'
• You, in Spanish
• Yucatán "you"
• You, in Uruguay
• Yucatán ''you''
• Formal 'you,' in Spanish
• "ÀC—mo est‡ __?"
• You: Sp.