Possible Clues:

• Not to a great extent
• Not much to go under this, but it helps to a certain degree
• Letters were guide to gold - go slow!
• John with Robin
• Rich with humor
• In flames, let this not be at large
• Gene Roddenberry's long-running sci-fi TV and film series
• With 116-Down, she sang 'The Loco-Motion'
• 'A . . . . . . knowledge is a dangerous thing'
• 'Wee Smacker' Funny title